Foundry.
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SynPlan
The Discovery Dashboard
The agile starting point and dashboard for running Design-
Make-Test-Analyze (DMTA) cycles on the Synfini Foundry.
Establishes program objectives, customizable workflows, hypotheses, and serves as collaboration
center. Manages full Design-Make-Test-Analyze (DMTA) cycles. Takes novel targets to SynDesign and novel molecules – from any 3rd-Party system – to SynRoute and SynPlan.
SynDesign
Superior Accuracy Shown on Smaller Training Sets
Semi-Supervised ML learns molecular encoding from millions of molecules then can make predictions from more than fifty of them.
A neuro-symbolic, neuro-physical AI system for molecule generation and property prediction.
SynDesign accurately predicts molecule properties such as affinity, selectivity and ADME
properties using a semi-supervised, transformer-based machine learning technique. The
chemist-first, semantically constrained AI requires 90% less data than other systems giving
fewer ‘false designs’ & direct optimization for fast, energy-efficient training.
The only chemistry AI built to naturally interact with chemists.
SynRoute
AI Synthesis Planning
Empowering Chemists to develop routes for novel compounds, with the highest success rate of available synthetic planning tools.
An AI-driven synthesis planning tool that streamlines the complexity of
chemical synthesis. Generate and collaborate on synthesis designs &
routes in an integrated, chemist UX. Amplify human expertise and convert
concept into executable chemistry plans in less than 60 seconds. Highest
published route success rate (86%) on medicinal chemistry compounds.
Built for collaboration and feedback.
SynBuild
The Agile Chemistry Automation
- Reproducible digital processes validated for 1000s of reactions
- Transferable processes that work across scales (μg to 10g)
- High-throughout parallel synthesis of 10s to 100s of compounds
- Rapid access to results with reporting through platform UI
Revolutionizes the synthetic chemistry process with a collection of tools that address the critical challenges of reproducibility, scalability and efficiency. SynBuild digitizes laboratory chemistry across three hardware systems: SynJet screens and optimizes 30 reactions per hour at nmol scale; SynJetPro produces 100 compounds per day at mg scale through parallel synthesis; and AutoSyn produces gram scale compounds through multistep flow chemistry, rapidly producing key intermediates and scaled-up compounds.
SynDB
Virtual and Physical Connection
At the core of the Synfini platform, SynDB maintains aggregated, curated, validated &evolving chemistry data. The database has digital protocols for 60% of medicinal chemistry and is constantly growing from real-world drug discovery projects, resulting in a network effect of continuous improvement.